Core Facilities
Computational Genomics Core
This core provides the information technology and data analysis support for activities related to bioinformatics. The information technology component provides the necessary database structures and development expertise to assist a wide variety of projects. It provides developement expertise for creating web application interfaces to databases as well as standalone applications for interacting with database schemas. This core supports both internal and external projects via consulting and project management services.
The data analysis component provides the necessary expertise to analyze genetic data as it is generated by the DNA Resources Core or by individual investigators. Expertise in GWAS (genome-wide association study), linkage, segregation, linkage disequilibrium, association, and risk factor analyses is provided. Access to a centralized database and to all the necessary software is also provided.
DNA Resources Core
This core has several components. The DNA bank receives specimens from various studies, extracts DNA, and stores both original samples and extracted DNA. Quality control, organization, and efficiency are critical. We have the capability of initiating and storing lymphoblastoid cell lines. High-throughput genotyping provides the necessary speed, efficiency, and accuracy to perform genomic screens (with standard markers) in as little time as possible.
Genetic Studies Ascertainment Core
Ascertainment for genetic studies is a crucial and labor-intensive effort. The Genetic Studies Ascertainment Core offers a variety of services to Vanderbilt clinical and basic researchers interested in or currently conducting research involving genetic analysis of complex disorders. We can aid in the development and coordination of individual and family based genetic studies. The faculty and staff of the GSAC have expertise in the issues that need to be considered when setting up a genetic study and are qualified to discuss with individuals issues that might be raised by participation in a genetic study.
This core provides the information technology and data analysis support for activities related to bioinformatics. The information technology component provides the necessary database structures and development expertise to assist a wide variety of projects. It provides developement expertise for creating web application interfaces to databases as well as standalone applications for interacting with database schemas. This core supports both internal and external projects via consulting and project management services.
The data analysis component provides the necessary expertise to analyze genetic data as it is generated by the DNA Resources Core or by individual investigators. Expertise in GWAS (genome-wide association study), linkage, segregation, linkage disequilibrium, association, and risk factor analyses is provided. Access to a centralized database and to all the necessary software is also provided.
DNA Resources Core
This core has several components. The DNA bank receives specimens from various studies, extracts DNA, and stores both original samples and extracted DNA. Quality control, organization, and efficiency are critical. We have the capability of initiating and storing lymphoblastoid cell lines. High-throughput genotyping provides the necessary speed, efficiency, and accuracy to perform genomic screens (with standard markers) in as little time as possible.
Genetic Studies Ascertainment Core
Ascertainment for genetic studies is a crucial and labor-intensive effort. The Genetic Studies Ascertainment Core offers a variety of services to Vanderbilt clinical and basic researchers interested in or currently conducting research involving genetic analysis of complex disorders. We can aid in the development and coordination of individual and family based genetic studies. The faculty and staff of the GSAC have expertise in the issues that need to be considered when setting up a genetic study and are qualified to discuss with individuals issues that might be raised by participation in a genetic study.